By Dwayne McDuffie

Back to the long run 2 used to be the second one factor of the again to the long run comedian sequence by means of Harvey Comics.

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The Dinosaurs upward push again!

Perhaps the strangest experience of all of them! As document sends the workforce again to the Cretaceous Period... the 3rd geologic section of the Mesozoic period and the top of the Dinosaur Age!

In an attempt to avoid wasting earth from the impressive destruction of a large meteor, document transforms background and retains the dinosaurs alive. "Ouch-a-ma-goucha!" as document may possibly say, this case now threatens to ruin all mankind...TODAY!

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1973). Acta Chern. , 27, 2075 Ash, A. S. F. and Schild, H. O. Br. J. Pharmacol. , 27,427 Barlow, R. B. (1964). Introduction to Chemical Pharmacology, 2nd edn, London, Methuen Bell, P. H. and Roblin, R. O. (1942). J. Am. Chern. , 64,2905 Benesch, R. E. and Benesch, R. J. Am. Chern. , 77, 5877 Black, J. , Duncan, W. A. , Durant, G. , Ganellin, C. R. and Parsons, M. E. (1972). Nature (London), 236, 385 Black, J. , Duncan, W. A. , Emmett, J. , Ganellin, C. , Parsons, M. E. and Wyllie, J. , (1973).

One receptor type, designated Hi by Ash and Schild (1966), mediates histamine -induced contraction of smooth muscle of the small intestine and bronchi. A second receptor type, designated H2 and characterised by Black et al. (1972), mediates the action of histamine in vivo in stimulating gastric acid secretion, and in vitro in increasing the rate of beating of the guinea·pig atrium. Many other actions of histamine have also been shown to involve Hi or H2 receptors but they need not concern us here (for a recent review see Chand and Eyre, 1975).

Med. , 16,620 Ganellin, C. R. (1974). In Molecular and Quantum Pharmacology; Proceedings of the 7th Jerusalem Symposium On Quantum Chemistry and Biochemistry (ed. E. D. Bergman and B. Pullman), Dordrecht, Reidel, p. 43 Ganellin, C. , Pepper, E. , Port, G. N. 1. and Richards, W. G. (l973a). J. Med. , 16,610 Ganellin, C. , Port, G. N. 1. and Richards, W. G. (1973b). J. Med. , 16,616 Gill, E. W. (1965). Drug receptor interactions. In Progress in Medicinal Chemi:s1ry (ed. G. P. Ellis and G. B. West), Vol.

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